Indications / Uses :
Treatment of hypertension.
Should be taken on an empty stomach: Take 15 min before meals. However, when initiating therapy, 1st dose should be given at bedtime.
Patients with known hypersensitivity to ACE inhibitors or with a history of angioneurotic edema.
Special Precautions :
Administer with caution in the elderly and in patients with renal disease. Increased age and impaired renal function may decrease the urinary excretion of imidapril and its metabolites.
Imidapril should be used with caution in patients with unilateral or bilateral renal artery stenosis since increase in blood urea nitrogen and serum creatinine may occur.
In general, ACE inhibitors should be used with caution in patients with sodium depletion or hypovolemia and those undergoing dialysis, major surgery or during anesthesia since severe hypotension may occur.
Use in lactation: Imidapril is excreted in breast milk therefore, avoid use of the drug in nursing mothers.