Amlokard 5Mg Tablet
Description : Each 5- and 10-mg tablet contains amlodipine besilate equivalent to amlodipine 5 and 10 mg, respectively.
Amlodipine besilate is a 1, 4-dihydropyridine derivative, long-acting calcium channel blocking agent which is used in the management of angina pectoris and hypertension.
Indications / Uses : Management of angina pectoris, hypertension and Prinzmetal angina.
Administration : May be taken with or without food.
Contraindications : Hypersensitivity to Amlokard and other dihydropyridines and those with severe hypotension, aortic valve stenosis, chronic idiopathic constipation, severe liver impairment and coronary artery disease.
Special Precautions : Patients with Renal Impairment: There is no need to adjust the dose of amlodipine in patients with renal disease since once-daily administration of Amlokard is found to be suitable for all degrees of renal functions.
Patients with Hepatic Impairment: In the presence of hepatic impairment, dosage of amlodipine should be adjusted to 2.5 mg/day.
Use in lactation: There is no available data yet confirming the excretion of amlodipine in breast milk. Caution should be taken when giving Amlokard to lactating mothers.
Use in children: In a study done among hypertensive children with mean age of 12 years, amlodipine was found to effectively lower systolic blood pressure. The safety and efficacy of amlodipine in children <6 years has not yet been established.
Use in the elderly: Amlodipine is well tolerated in elderly hypertensive patients at a dose of 2.5 mg/day.