Description
GABIX 300MG TABLET
Description : Gabix is a new antiepileptic drug that is structurally similar to the neurotransmitter gamma-aminobutyric acid (GABA) and the endogenous amino acid L-leucine. Chemically, gabapentin is 1-(aminomethyl)-cyclohexaneacetic acid. Its molecular formula is C9H17NO2.
Indications / Uses : Epilepsy: Adjunctive therapy in the treatment of partial seizures with or without secondary generalization in adults and children =6 years.
Monotherapy in the treatment of partial seizures with or without secondary generalization in adults and adolescents =12 years.
Neuropathic Pain: Postherpetic neuralgia (PHN), peripheral diabetic neuropathies and trigeminal neuralgia in adults.
Administration : May be taken with or without food.
Contraindications : Patients with known hypersensitivity to gabapentin or any of the components of Gabix.
Special Precautions : Patients should be monitored for signs of suicidal ideation and behaviors and appropriate treatment should be considered. Patients (and caregivers of patients) should be advised to seek medical advice and should watch for signs of suicidal ideation or behavior.
If a patient develops acute pancreatitis under treatment with gabapentin, discontinuation of gabapentin should be considered.
Abrupt withdrawal of anticonvulsant agents in epileptic patients may precipitate status epilepticus.
As with other antiepileptic medicinal products, an increase in seizure frequency or the onset of new types of seizures with gabapentin.
Gabapentin should not be considered a treatment of absence seizures. It may exacerbate these seizures in some patients. Consequently, gabapentin should be used with caution in patients who have mixed seizure disorders that include absence seizures.
Effects on the Ability to Drive or Operate Machinery: Patients should be advised neither to drive a car nor to operate complex machinery until they have gained sufficient experience on gabapentin.
Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Gabapentin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in lactation: Gabapentin is excreted into breast milk following oral administration. The effect on the nursing infant is unknown. Therefore, gabapentin should be used in nursing women only if the potential benefits clearly outweigh the risks.
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