Godex Ds Capsule
Description : Each capsule contains carnitine orotate 300 mg, 17 amino acid 25 mg, adenine hydrochloride 5 mg, pyridoxine hydrochloride (vitamin B6) 50 mg, riboflavin (vitamin B2) 1 mg and cyanocobalamin (vitamin B12) 250 mcg.
Pyrimidine nucleotide precursor, orotate, combined with pharmaceutically acceptable salts cationic carnitine, carnitine HCl, 17 amino acids and more agents (adenosine, pyridoxine HCl, cyanocobalamin) with protective or supportive activity relative to mitochondrial structure and function.
Carnitine Orotate, the molecular formula is C7H16NO3C5H3N2O4:C12H19N3O7; the molecular weight is 333.34 g/mol, which when administered in vivo has a synergistic effect. It increases solubility and is more easily absorbed by the injured cells, rather than the administration of carnitine individually.
Cyanocobalamin (vitamin B12) is 5,6-dimethyl-benzimidazolyl cyanocobamide; molecular formula is C63H88 C0N14O14P. The cobalt content is 4.34%. The molecular weight is 1355.39. Vitamin B12 is bound to intrinsic factor during transit through the stomach; separation occurs in the terminal ileum in the presence of calcium and vitamin B12 enters the mucosal cell for absorption. It is then transported by the transcobalamin binding proteins.
Indications / Uses : Treatment of acute & chronic hepatitis, fatty liver, liver cirrhosis, liver intoxication by drug or chemical substances, mitochondrial dysfunctions.
Administration : May be taken with or without food.
Contraindications : Hypersensitivity to any of the components of Godex DS. Severe renal dysfunction (serum creatinine >3 mg/100 mL).
Special Precautions : Long-term use of large doses of pyridoxine is associated with the development of severe peripheral neuropathies.