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Indications / Uses :
Treatment of non-insulin-dependent diabetes mellitus (NIDDM) not responding to dietary modification. As a monotherapy or in combination with a sulfonylurea product. In type I diabetic patients or insulin-deficient patients who are not adequately controlled, metformin may be combined with insulin.
Should be taken with food.
Renal impairment and liver failure because of an increased risk of hypoglycemia.
Patients with heart failure, recent myocardial infarction, dehydration, alcoholism or any other condition likely to predispose to lactic acidosis.
Special Precautions :
Renal impairment may also predispose patients to lactic acidosis. Regular renal and hepatic monitoring is essential.
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