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Indications / Uses : Reduces LDL-cholesterol, apolipoprotein B & triglycerides; increases HDL-cholesterol in the treatment of hyperlipidemias. Adjunct therapy in patients w/ homozygous familial hypercholesterolemia who have some LDL-receptor function. Primary prophylaxis of CV events in patients w/ multiple risk factors.
Administration : May be taken with or without food.
Contraindications : Active liver disease or unexplained persistent elevations of serum transaminases. Pregnancy, women of childbearing potential, lactation.
Special Precautions : Perform liver function tests & monitor for creatine phosphokinase & transaminase elevations. Avoid alcohol consumption. Temporarily discontinue therapy in patients w/ an acute, serious condition suggestive of a myopathy or renal failure secondary to rhabdomyolysis.