CELCOXX 400MG CAPSULE
Description : Celecoxib belongs to a new class of arthritis/analgesic medication called “COXIBS”.
Celecoxib is 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide and is a diaryl-substituted pyrazole. The molecular formula for celecoxib is C17H14F3N3O2S.
Indications / Uses : Treatment of RA, post-op/dental pain, acute flare pain of osteoarthritis, pain including dysmenorrhea & familial adenomatous polyposis (FAP).
Administration : May be taken with or without food: Dose for OA/RA may be given w/ or w/o meals, but doses for FAP must be given w/ meals.
Contraindications : Asthma, urticaria, allergic-type reaction to sulfonamides, aspirin or other NSAIDs; renal impairment w/ CrCl <30 mL/min; severe hepatic impairment, heart failure & inflammatory bowel disease; history of MI or stroke; peri-op period undergoing cardiac or major vascular surgery.
Special Precautions : Ulceration, bleeding & perforation of GIT; fluid retention, HTN or heart failure; dehydration; hepatic impairment. Renal papillary necrosis & other renal injury. Monitor BP during initiation of therapy. Pregnancy & lactation.